Nox proteins in signal transduction

Nox proteins in signal transduction.

The NADPH oxidase (Nox) family of superoxide (O(2)(*-)) and hydrogen peroxide (H(2)O(2))-producing proteins has emerged as an important source of reactive oxygen species (ROS) in signal transduction. ROS produced by Nox proteins Nox1-5 and Duox1/2 are now recognized to play essential roles in the physiology of the brain, the immune system, the vasculature, and the digestive tract as well as in ...

Signal Transduction: Rho-like Proteins in Plants

Plants lack the Rho and Rac/Cdc42 GTPases that are so important in diverse signal transduction processes in animals. A plant-specific group of Rho-like proteins - Rops - shows striking similarities to their animal relatives, but also exciting differences in their regulation and signal transduction.

Role of G proteins in signal transduction.

Modular binding domains in signal transduction proteins

The transduction of a signal is a change in form of the signal as it is passed from one carrier to another. The root "duce" means"to lead" in Latin; thus, a signal is led through a cell by steps of transduction (the same root is in the words seduce and duct as well as II Duce). The earliest transduction steps that were elucidated involved massive release of small molecule "second messengers", o...

TRP channel proteins and signal transduction.

TRP channel proteins constitute a large and diverse family of proteins that are expressed in many tissues and cell types. This family was designated TRP because of a spontaneously occurring Drosophila mutant lacking TRP that responded to a continuous light with a transient receptor potential (hence TRP). In addition to responses to light, TRPs mediate responses to nerve growth factor, pheromone...